CyGenTiG is an international collaborative scientific programme to develop techniques for controlling living cells, including human cells, with light. Compared to drugs or physical interventions, light has huge advantages; it can be shone only when it is needed, it can be controlled with high accuracy, and it can be switched off the instant its work is done. Although at an early stage, research into light-mediated control of cells, or ‘optogenetics’ as it is called, has the potential to be a major technology in healthcare of the future.
CyGenTiG is combining expert knowledge from leading research institutions and companies throughout Europe.
3rd Optogenetic Technologies and Applications Conference
Talk: Jamie Davies – Goals, purpose, agency: going beyond engineering metaphors to work with, as well as on, biological systems
Advances in Cell & Tissue Culture (by Kirkstall Ltd
Talk: Jamie Davies – The DIY human: the art of making human tissues from stem cells.
Jamie Davies gives a talk at the Royal Society of Biology.
Edinburgh Group Meeting
The team met in Edinburgh to discuss upcoming collaborations and future projects. We covered light sensitive cell construction and testing, imaging and illumination, modeling and automated closed loop control and had lots of good discussions and positive feedback.
Review article on optogenetic tools for bacteria
Model reduction of metabolic networks for the integration of kinetic models into Design-Built-Test-Learn cycles
Control of cell death through light
Burden of engineered gene expression in mammalian cells
Paper on Engineering of Pattern Formation
Paper on pattern formation using an optogenetic cell-in-the-loop approach